N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine

N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine is a synthetic small molecule peptide derivative with the molecular formula C15H26N4O7 and a molecular weight of 374.39 g/mol[1][2][4]. It is classified as an experimental compound and has not been approved for clinical use in any country[2]. The compound has been reported to interfere with PAICS protein, an enzyme involved in de novo purine biosynthesis, thereby reducing the accumulation of SAICAR and SAICAr intermediates[3][6]. This suggests potential utility as a biochemical tool or research probe for studying purine metabolism or related pathways. There are no known clinical indications, patents, or advanced development programs associated with this molecule.

Other names

Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine(2S)-2-(2-aminoacetamido)-6-{[(1R)-1-{[(1R)-1-carboxyethyl]carbamoyl}ethyl]carbamoyl}hexanoic acid